Transforming Diabetes Management for Your Health Plan Members

Enhance your diabetes care strategy with SequelConnect, a program designed to help improve health outcomes and quality metrics while reducing costs for high-risk insulin-dependent members.

The Challenges Health Plans Face with Diabetes Management

Health plans are under increasing pressure to deliver innovative, cost-effective diabetes solutions that meaningfully impact both clinical outcomes and the bottom line.

Rising Costs of Insulin-Dependent Members

Members requiring insulin therapy - 25% of all people with diabetes - account for a high percentage of your diabetes-related healthcare spend.¹ Frequent hospitalizations and complications may cost up to $37,074 per member annually.²

Quality Metric Improvement Challenges

Your HEDIS scores and Star Ratings are directly impacted by diabetes care metrics, including A1C control, hospitalization rates, and member satisfaction. SequelConnect offers a fresh approach to diabetes management and creates opportunities for improved scores.

Member Engagement and Retention

Employers increasingly expect innovative benefits that improve health and satisfaction, raising the bar for acquisition and retention. SequelConnect helps you support your entire employer portfolio.

Key Program Elements

SequelConnect: The Missing Piece in Your Diabetes Strategy

SequelConnect addresses this challenge head-on by identifying high-cost members who use insulin and connecting them with insulin therapy technology.

Member Identification and Enrollment

Proactive identification of eligible members through claims data analysis
Targeted education and outreach
Simple digital enrollment process

Clinical Support and Enhanced Care

Virtual access to specialized providers
Personalized training with Certified Diabetes Care and Education Specialists
24/7 customer support

Simplified Access and Fulfillment

Prior authorization support
Delivery direct-to-home or retail pharmacy pickup
Automated refills & prescription management

Technology-Enabled Diabetes Management⁵

Accurate delivery and adjustment of basal insulin
Discreet management via twiist App and Apple Watch
Personalized settings enables members to manage their diabetes

The program features outlined above are included as part of the twiist AID System experience. Features may differ if a member is prescribed a different AID system.

SequelConnect Advantage:

Featuring the twiist AID System - a Customized Approach for Members

The twiist AID System represents a significant advancement in diabetes care technology, designed to align with the American Diabetes Association's preferred standard of insulin delivery³.

The twiist Automated Insulin Delivery (AID) System is for people with type 1 diabetes, 6 years of age and above, available with a prescription, only in the U.S. Pursuing type 2 indication. Visit twiist.com for more information.

Real World Evidence

Experience the first Automated Insulin Delivery (AID) system built on an algorithm created by and for people with diabetes.

The Loop algorithm, on which twiist Loop is based, has demonstrated significant clinical benefits in real-world studies - a sustained average A1C of 6.5%⁴ and an 80% reduction in severe hypoglycemia^4-6.
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Learn More

Advancements in Diabetes Care

The novel iiSure™ technology in the twiist™ Automated Insulin Delivery (AID) System provides advanced accuracy and faster occlusion detection than other AID systems⁸.

The technology uses sound waves to directly measure the volume of insulin delivered and includes 4 checkpoints along the way to help ensure accurate delivery—something no other AID system can do.⁷

Featuring the twiist AID System - a Customized Approach for Members

Simple Implementation with Minimal Administrative Burden

SequelConnect requires minimal contracting efforts and integrates seamlessly with your existing systems. Direct billing through your pharmacy benefit manager (PBM) facilitates easy adoption and activation, allowing you to quickly deliver SequelConnect to members who need it most.

AID Systems Drive Value

94.7%

Engagement

AID system users continued with the device after 6 months.⁹

Results obtained with the Loop algorithm using a non-twiist device.

$18.7K

Expected Savings Per Member

By helping to reduce severe hypoglycemic events and diabetes-related hospitalizations, SequelConnect can deliver meaningful cost reductions.²

SAVINGS CALCULATOR

See How Much Health Plans Can Save With SequelConnect

Discover the impact SequelConnect can have on your company's bottom line. Use our calculator to estimate your organization's potential cost savings when implementing SequelConnect, our innovative diabetes management program.

How many lives does your organization cover?

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The estimated annual savings amount calculated is based on the estimated number of covered lives, average percentage of the U.S. population living with diabetes requiring insulin, and estimated enrollment rate. Please contact Sales for details and exact calculations as it relates to your business. Actual results may vary.

Close the Gap in Your Diabetes Strategy Today

You've done a great job building a diabetes management program. Now it's time to make it phenomenal. SequelConnect provides the missing pieces to help your insulin-dependent members achieve better health¹ while reducing your overall costs.

Fang M, et al. Trends in Diabetes Treatment and Control in U.S. Adults, 1999 -2018. N Engl J Med 2021;384(23):2219 -28
Sequel - Data on File
American Diabetes Association, Diabetes Care, January 2025, Volume 48, Supplement 1
Lum JW, et al. A Real-World Prospective Study of the Safety and Effectiveness of the Loop Open Source Automated Insulin Delivery System. Diabetes Technol Ther 2021;23(5):367–75. Results obtained with the Loop algorithm using a non-twiist device
The Loop Observational Study Design The Jaeb Center for Health Research, in collaboration with Stanford University and Tidepool conducted an open-enrollment, observational study to collect data on the Loop System (ClinicalTrials.gov Identifier: NTC03838900).This study collected and analyzed data on the efficacy, safety, usability, and quality of life/psychosocial effects of the Loop System in patients diagnosed with type 1 diabetes (T1D) who were using insulin (pump therapy or multiple daily injections) and were using Loop or had plans to begin using Loop. Tidepool Loop is based on the same algorithm as Loop. Results obtained using Tidepool guardrails on a non-twiist™ device.
Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide. The twiist Automated Insulin Delivery (AID) System is for people with type 1 diabetes, 6 years of age and above, available with a prescription, only in the U.S. Visit twiist.com/safety for important safety information.
1. Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide ; 2. Insulet - Omnipod 5 Automated Insulin Delivery System User Guide ; 3. Medtronic - MiniMed 780G system User Guide ; 4. Beta Bionics - iLet Bionic Pancreas System User Guide ; 5. Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide ; 6.Tandem Diabetes Care - Tandem Mobi System User Guide.
Calculation based on a comparison of the following IFUs. The following reported 1 U/hr basal rate: Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide ; Insulet - Omnipod 5 Automated Insulin Delivery System User Guide ; Medtronic - MiniMed 780G system User Guide ; Beta Bionics - iLet Bionic Pancreas System User Guide. The following reported 2 U/hr basal rate: Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide ; Tandem Diabetes Care - Tandem Mobi System User Guide.
Wong JJ, et al. Discontinued Use of the Loop Insulin Dosing System: A Mixed-Methods Investigation. Diabetes Technol Ther 2022;24(4):241–8.